Urine is responsible for carrying out soluble forms of waste from the body. It also carries chemical substances that are released by organs in case of an infection or disease. Urine also carries organic acids which are easier to extract and test compared to plasma level tests.
Urine organic acid test accurately detects a wide range of compounds present in the urine. It acts as a highly dependable diagnostic test for organic acidemias like propionic, methylmalonic, and isovaleric acids.
The organic acid test also accurately detects the presence of glutaric acid, a progressive neurotoxic defect that occurs during a biomolecule conversion. Abnormal fat compounds in the urine can indicate fatty acid oxidation defects. Similarly, the presence of succinylacetone is a strong indicator of tyrosinemia. Tricky to detect organic acids like lactic acid and ketones are also detectable in a urine organic acids test.
The test is also used to detect genetic disorders caused by insufficient enzyme production in the body.
So what problems and imbalances can an organic acids test identify?