Function of the liver
One of the major roles of the liver is detoxification. It works to convert fat-soluble toxins into water soluble substances that can be excreted from the body. It does this via a two-step process designated phase I and phase II.
When the function of the liver is sub-optimal, toxins can build-up and poison the body.
Conditions that may be associated with an imbalance in liver function include:
Adverse drug reactions
Dysfunction of the immune system
Headaches or migraines
Motor neuron disease
Multiple chemical sensitivities
Recent data also suggests that close to 100% of autistic children have irregularities of liver detoxification. One of the pathways that is highly affected is phase II sulfation; a process which helps process phenolic foods and many other chemicals.
The Functional Liver Detoxification Profile (FLDP) challenges the liver’s Phase I and Phase II detoxification capacity with low doses of caffeine, aspirin and paracetamol.
Phase I Detoxification: caffeine clearance.
Phase 2 Detoxification: measures the detoxification pathways of glucuronidation, gylcination, glutathionation, and sulfation.
Specific measurements of the different phases of liver detoxification including phase I and phase II (glycination, glucuronidation, sulfation and glutathionation) are obtained, guiding the design of effective and specific therapeutic strategies which can optimize liver function to improve your health.