The Adrenal Fatigue Test: What is It and Is It Worthwhile? - MyVitalHealthSolutions

The Adrenal Fatigue Test: What is It and Is It Worthwhile?

In today’s fast-paced world, stress has become an inevitable part of daily life. Whether it’s the demands of work, relationships, or other responsibilities, prolonged stress can take a toll on our bodies. One question that gets asked in alternative medicine is………. Is there such a thing as adrenal fatigue? —a condition believed to result from chronic stress and characterised by a range of symptoms. 

Proponents of naturopathy and functional medicine often advocate for addressing adrenal fatigue through natural remedies like various lifestyle changes, dietary adjustments, and supplements. But amidst the buzz surrounding this condition, the question arises: is the adrenal fatigue test worthwhile? How are adrenals measured in conventional medicine and in functional medicine? What are the challenges in performing adrenal dysfunction test?

Understanding Adrenal Dysfunction And The Stages of Adrenal Fatigue

Before delving into the questions about adrenal fatigue test, it’s essential to understand what is the function of adrenal glands and purported symptoms of adrenal fatigue. 

Adrenal fatigue is a term used to describe a collection of symptoms such as fatigue, body aches, nervousness, sleep disturbances, and digestive issues, believed to be caused by chronic stress leading to dysfunction of the adrenal glands. These small glands located on top of the kidneys are responsible for producing hormones like cortisol, which regulates stress response, metabolism, and immune function. 

Adrenal fatigue is often conceptualised in stages, ranging from mild to severe dysfunction. These stages may include:

Stage 1: Alarm Reaction

Initial response to stress, characterised by heightened cortisol levels.

Stage 2: Resistance

Continued exposure to stress leads to cortisol dysregulation and fatigue.

Stage 3: Adrenal Exhaustion

Chronic stress depletes adrenal reserves, leading to fatigue, burnout, and hormone imbalances.

Stage 4: Adrenal Failure

Severe depletion of adrenal function, resulting in profound fatigue and potentially serious health complications.

Common Symptoms of Adrenal Fatigue

Adrenal fatigue can lead to a variety of symptoms. AFS has four stages, and these symptoms can change as you move through the different phases as well. Some of the most common symptoms of adrenal fatigue include:

  • Constant anxiety
  • Depression
  • Feeling fatigued all the time.
  • Loss of appetite or craving salty/sugary foods
  • Weight gain or weight loss for no known reason
  • Obesity
  • Nausea/vomiting
  • Muscle pain/muscle weakness
  • Blood pressure issues
  • Health issues relating to a hormone imbalance. 

Do You Need an Adrenal Fatigue Test?

One aspect that has drawn attention to adrenal fatigue is its prevalence, particularly among females. Women, who often juggle multiple roles and responsibilities, may find themselves more susceptible to the effects of chronic stress on adrenal function. 

Symptoms such as fatigue, irritability, and hormonal imbalances are frequently reported by women experiencing adrenal fatigue, leading many to seek solutions beyond conventional medicine. 

So if you’ve been searching for adrenal function tests, adrenal stress tests, or adrenal imbalance tests; you probably need to see an Adrenal Fatigue Specialist who possesses in-depth knowledge on how to diagnose adrenal fatigue.

The Challenges of Testing Adrenal Fatigue

Diagnosing adrenal fatigue can be challenging as there is no single, definitive test. However, naturopathy and functional medicine offer alternative approaches to test and address adrenal fatigue, focusing on holistic healing and personalised care. 

Central to these approaches is the belief that supporting the body’s adrenal function is key to overcoming adrenal fatigue. This often involves a combination of dietary modifications, stress management techniques, targeted supplementation, and lifestyle adjustments.

Conventional Medicine Test for Adrenal Fatigue!

Adrenal Fatigue has been recognised as a distinct clinical syndrome since the turn of the 20th century. But most doctors are unfamiliar with this condition. That is because it is difficult to diagnose by traditional blood tests as there is no specific blood test for adrenal fatigue. 

Normal blood tests detect severe changes in adrenal hormones, such as Addison’s Disease. However, Addison’s disease afflicts only 4 out of 100,000 and is often the result of an autoimmune disease or infectious origin. Blood tests are also useful to detect extreme, excessive levels of adrenal hormones, a condition known as Cushing’s disease.

 Let’s examine this in more detail. The ACTH (adrenocorticotropic hormone) challenge test is the conventional test used to examine the signs of adrenal fatigue in blood tests. This test recognises extreme underproduction or overproduction of hormone levels.

 Usually test results fall into a normal range for someone with Adrenal Fatigue, causing this condition to be labelled adrenal fatigue syndrome instead of a disease. Symptoms of non-Addison adrenal malfunction, meanwhile, can start to present itself after a 15 percent deviation from the mean on the bell curve. Therefore, the adrenal glands could be functioning anywhere from 15 to 48 percent below the norm and not be detected by the ACTH test.

 To sum it up, adrenal hormones are low in the case of Adrenal Fatigue. But they are still within the “normal” range and not low enough to warrant the diagnosis of Addison’s disease. Such “normal” levels of adrenal hormones do not mean that the patient is free from adrenal dysfunction. Conventional doctors are not taught the significance of subclinical Addison’s disease, or Non-Addison’s Hypoadrenia (commonly referred to as Adrenal Fatigue). Blood tests misguide them. As a result, patients tested for adrenal functions are told they are “normal”. But their adrenal glands are performing sub-optimally, with clear signs and symptoms as the body cries out for help and attention.

Naturopathic Tests for Adrenal Fatigue!

1. Salivary Hormone Test

Salivary hormone testing is a diagnostic tool utilised in both naturopathic and functional medicine practices to assess hormonal balance and function. Unlike traditional blood tests, which measure hormone levels in the bloodstream, salivary hormone testing offers a non-invasive and convenient method of evaluating hormone levels directly in saliva samples. 

In naturopathic and functional medicine, hormonal imbalances are recognised as potential contributors to a wide range of health issues, including fatigue, weight gain, mood disturbances, sleep disturbances, and reproductive disorders. Saliva Testing for Adrenal  insufficiency provides valuable insights into these imbalances by measuring the levels of key hormones such as cortisol, DHEA (dehydroepiandrosterone), oestradiol, progesterone, and testosterone.

The process of saliva test for adrenal glands typically involves collecting multiple saliva samples throughout the day, as hormone levels fluctuate in a circadian rhythm. This comprehensive approach allows practitioners to assess hormone levels at different times while checking adrenal function and gain a more accurate picture of hormonal patterns and fluctuations. Patients may be instructed to collect saliva samples upon waking, before meals, and before bedtime to capture variations in hormone secretion throughout the day. 

Once collected, saliva samples are analysed for adrenal function test using advanced laboratory techniques to quantify hormone levels accurately. The adrenal fatigue lab results provide valuable information about the patient’s hormonal status, including whether hormone levels are within optimal ranges or if imbalances exist.

In naturopathic and functional medicine, the interpretation of adrenal fatigue test results is often guided by principles of holistic health and personalised care. Practitioners consider not only the numerical values of hormone levels but also the patient’s symptoms, lifestyle factors, and overall health status. This holistic approach allows for targeted interventions aimed at restoring hormonal balance and promoting optimal health and well-being.

Based on the results of salivary hormone testing, naturopathic and functional medicine practitioners may recommend individualised treatment plans to address hormonal imbalances. These treatment plans may include dietary modifications, lifestyle changes, stress management techniques, herbal remedies, nutritional supplements, and bio-identical hormone therapy, depending on the specific needs of the patient.

One of the key advantages of adrenal function saliva test is its ability to detect hormone imbalances that may go unnoticed with traditional blood tests. Saliva testing measures the bioactive, free fraction of hormones, which is more reflective of hormone activity at the tissue level compared to total hormone levels measured in blood. This nuanced approach allows for more accurate assessment and targeted intervention to address hormonal imbalances effectively.

 Overall, salivary hormone testing plays a valuable role in naturopathic and functional medicine practices by providing insight into hormonal imbalances and guiding personalised adrenal fatigue treatment options. By assessing hormone levels directly in saliva samples, practitioners can tailor interventions to support optimal hormone balance and promote overall health and well-being for their patients.

2. Organic Acids Test

Organic acids testing (OAT) is a comprehensive diagnostic tool used in naturopathic and functional medicine to assess metabolic function and identify underlying imbalances that may contribute to a variety of health issues. This specialised testing analyses urine samples to measure levels of various organic acids, which are metabolic byproducts produced during biochemical processes in the body. 

In naturopathic and functional medicine, the focus is on identifying and addressing the root causes of health concerns rather than merely treating symptoms of adrenal fatigue. Organic acids testing provides valuable insights into metabolic pathways, nutrient deficiencies, oxidative stress, detoxification capacity, neurotransmitter metabolism, and gut microbial balance.

The process of organic acids testing involves collecting a urine sample from the patient, typically over a 24-hour period. This comprehensive sampling allows for the measurement of a wide range of organic acids, providing a detailed assessment of metabolic function. The urine sample is then sent to a specialised laboratory for analysis using advanced mass spectrometry techniques.

The results of organic acids testing offer a wealth of information about the patient’s metabolic status and potential imbalances. Naturopathic and functional medicine practitioners use this test as one of the most effective adrenal fatigue testing methods to develop personalised treatment plans aimed at addressing underlying issues and optimising health and well-being.

One of the key advantages of organic acids testing for cortisol and adrenal fatigue is its ability to detect metabolic imbalances and nutrient deficiencies that may not be evident through conventional testing methods. By measuring levels of specific organic acids, practitioners can identify areas of dysfunction within metabolic pathways and tailor interventions accordingly.

 Organic acids testing is particularly useful in the assessment of conditions such as chronic fatigue syndrome, fibromyalgia, mood disorders, autism spectrum disorders, gastrointestinal disorders, and metabolic disorders. By gaining insight into metabolic function, practitioners can target interventions to support optimal health and improve patient outcomes.

Treatment strategies based on organic acids testing results may include dietary modifications, targeted supplementation, lifestyle changes, detoxification support, and addressing underlying gut imbalances. By addressing metabolic imbalances and supporting the body’s natural ability to heal, Adrenal Fatigue Specialists aim to restore balance and promote overall health and well-being.

 In conclusion, organic acids testing is a valuable tool in naturopathic and functional medicine practices, providing insight into metabolic function and guiding personalised treatment approaches. By assessing levels of specific organic acids in urine samples, practitioners can identify underlying imbalances and develop targeted interventions to support optimal health and wellness for their patients.

 One common recommendation for addressing adrenal fatigue is the adoption of Natural remedies for adrenal fatigue such as a personalised adrenal fatigue diet. This diet typically emphasises whole, nutrient-dense foods while minimising processed foods, caffeine, sugar, and alcohol. The adrenal fatigue diet argues that certain nutrients play a crucial role in supporting adrenal function and reducing stress on the body. Foods rich in vitamins C and B complex, magnesium, and omega-3 fatty acids are often recommended to nourish the adrenal glands and promote overall well-being.

In addition to dietary changes, Naturopath Domenic Pisanelli, an Adrenal Fatigue Specialist, often suggests the best supplements for adrenal fatigue to support adrenal health. These specific supplements may include adaptogenic herbs like ashwagandha, rhodiola, and licorice root, which are believed to help the body adapt to stress and promote balance. Other supplements such as vitamin D, magnesium, and omega-3 fatty acids may also be recommended to address nutrient deficiencies commonly associated with adrenal fatigue.

While the concept of adrenal fatigue and its associated treatments may resonate with many individuals experiencing chronic stress and fatigue, the scientific evidence supporting its validity remains controversial. Critics argue that adrenal fatigue is not recognised as a legitimate medical diagnosis by mainstream medicine and that its symptoms overlap with other conditions such as depression, anxiety, and thyroid disorders.

While some individuals may find relief from adopting an adrenal fatigue diet or taking supplements, others may not experience significant improvements. It’s essential to consult with a qualified healthcare professional before embarking on any treatment regimen for adrenal fatigue, as underlying medical conditions may need to be addressed.


The adrenal fatigue testing methods and associated adrenal fatigue treatment options are a topic of much debate within the realm of alternative medicine. While some individuals swear by the effectiveness of dietary changes, supplements, and lifestyle modifications for addressing adrenal fatigue symptoms, others remain sceptical of its validity. Ultimately, the decision to pursue testing and treatment for adrenal fatigue should be made in consultation with an Adrenal Fatigue Specialist who can offer personalised guidance based on individual needs and medical history. Whether or not the adrenal fatigue test is worthwhile is a question that remains open to interpretation, and further research is needed to shed light on this complex issue.